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Welcome to the Wiki aims to be a technical resource for the replication of biological components through tissue engineering. Topics for this site will include the materials and techniques currently being tested and used in the field of bio-printing. Additionally, we intend on covering current developments in the bio-printing community, such as the creation of a 3d-print exchange by the National Institutes of Heath (NIH).

What is Biofabrication?

Biofabrication is a programmed creation of tissues and organs that contend with health threats in Medicine. It utilizes the 3D printing which is also known as the theory of additive manufacturing. Its main objective is to merge gels, cells and fibres into a solo construct that can substitute an ailing or wounded tissue.

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Breakthrough in Biofabrication of replacement body parts

The QUT (Queensland University of Technology) biofabrication team has been making a name for itself through printing mechanically reinforced, tissue engineered constructs in order to restore the human body parts, in 3D. As published in Nature Communications, the biomedical engineers explained how they had strengthen soft hydrogels by printing a 3D scaffold.

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Cosmetic ingredients produced by Biofabrication

According to a scientist that works in the field, the raw materials that produce both living and nonliving biological ingredients for personal care products will be Living cells, organic molecules and the like.

A new research carried out in Germany, what makes 3-D printed algae a reality is using the hydrogel substructures. A team of researchers together with Dr. Anja Lode of the Centre for Translational Bone, Joint and Soft Tissue Research at the Dresden University of Technology as well as the University’s Institute of Food Technology have published their technical findings in the journal of Engineering in Life Sciences. As explained by Brian Krassenstein in his article on the scientific development for, “This means that not only can animal tissue be printed, but so too can plant tissue, or perhaps even a combination of both animal and plant cells via coculturization process”.

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Netherlands uses 3D printing for Biofabrication

The Utrecht Biofabrication Facility will shortly accomodate an extraordinary set of 3D bioprinters and it will be able put down living cells on a substrate layer-by-layer, and in this way renovating three dimensional organs. There are loads of noteworthy budding applications for the said machine in the medical field. For example, people who have bone defects could obtain specially made prosthetics that will fill up the gaps caused by their missing tissues flawlessly. The magnetic resonance imaging or computed tomography scans will gather the blueprints for each medical aid, and the one who will generate the needed prosthetics based on these very specific measurements are the printers.

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Tissue Engineering and Regenerative Medicine

The development of biomaterials effected to tissue engineering. It is also the practice of combining scaffolds, cells, and biologically active molecules into functional tissues. Its goal is to assemble functional constructs that restore, maintain, or improve damaged tissues or whole organs.

Regenerative medicine, on the other hand, refers to a broad field that includes tissue engineering, but also includes research on self- healing. The terms “tissue engineering”, and “regenerative medicine” have so identical, as the field aims to cure instead of treat for intricate, often chronic, diseases.

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Bioprinting is coming of age

An extension of 3D printing, which is used in medicine and healthcare, is the bioprinting. Prosthetics have been receiving 3D treatment and is becoming cheaper and more functional but with bioprinting it takes 3D printing well inside the body so that veins, bones and soon organs can be printed. This will transform the effectively the drug development and availability of organ transplants.

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From Science Fiction to Reality: The Dawn of the Biofabricator

Science is certainly making a move to be closer to the world of science fiction. Just a year ago, a man that was paralyzed was able to walk again subsequent to his cell treatment that linked a gap in his spinal cord. Heaps of human beings have experienced bionic eyes implantation, and it is likely to enhance them to perceive into the ultraviolet or infra-red. And with thoughts alone, amputees have the power over a bionic implant. In the meantime, we are on our way to printing body sections. Created by the beauty and awesomeness of the tools of technology, we are now seeing a redesigning of the clinical setting. The evolution is paving way to a new strain of engineer, one instructed to connect the space between engineering on one part and further on biology. Biofabricator’s function is to set technical abilities in biology, materials and mechatronics with the medical sciences.

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Biofabrication Revolution of Science

What is Biofabrication?

Biofabricaion is the self-operating procedure by 3D printing for the fabrication of organs and tissues to determine or deal with the current health problems today. Biofabrication is also known as 3D printing but instead of printing non-living things, this kind of printing will generate living organisms. These printers utilize technology to merge fibres, gels and cells into a solo form that would substitute damaged or diseased organs and tissues. Why is Biofabrcation important?

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Advantage and Disadvantage of Tissue Engineering

Tissue engineering is an emerging technology that is intended to improve or to replace biological functions.

Tissue engineering uses a combination of cells, materials, engineering methods and the appropriate biochemical factors to improve biological functions or to replace them altogether. The coverage is very broad in the assortment of applications in the medical science fields. It can be used to replace a part of an organ or to completely replace the organ or the biological system and it is often associated with “regenerative medicine”.

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The coming of regenerative medicine: Stem cell therapy is on its way quicker than expected

Two ground breaking researches that were published by Haruko Obokata at the RIKEN Center for Development Biology will add another notch of controversial past for the Stem Cell research. The study demonstrated the transformation of adult mouse somatic cells into embryonic like stem cells with short dip in acid. The paper was put under investigation by both Japanese research institute and nature for potential credibility issues. The astonishing findings impressed the medical communities worldwide due to the resounding therapeutic implications.

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Tissue ‘scaffold’ technology could assist in rebuilding large organs

‘Scaffold’ technology is the new tissue that scientists have developed that will enable the engineering of large organs. This research was led by the Universities of Bristol and Liverpool and it has shown that it is possible for cells to combine with a special scaffold to produce living tissue in the laboratory. Hopefully, this can be implanted to patients as a way of replacing the diseased parts/organs of the body. To this date, the approach is limited to growing small pieces of tissue, as larger dimensions reduce the oxygen supply to cells in the centre.

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start.txt · Last modified: 2015/12/14 07:39 by elena