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What is Biofabrication?

Biofabrication is a programmed creation of tissues and organs that contend with health threats in Medicine. It utilizes the 3D printing which is also known as the theory of additive manufacturing. Its main objective is to merge gels, cells and fibres into a solo construct that can substitute an ailing or wounded tissue.

Biofabrication is also a podium for an extensive array of tissues like nervous, cartilage, vascularized bone, skin and blood vessels, in conjunction with the whole organs such as the kidney, liver, heart and bladder. The finish invention is habitually compound and has a range of mechanisms plus structural and cellular components.

Biofabrication powerfully relies on 3D printing to precisely put matrix, cells, and resources in its proper place for culture and tissue. The following constructs can be employed as trial systems for the innovation of the latest drug, full understanding of cell’s life and for restoring organs and tissues that are mainly destroyed through disease or damaged.

The use of these 3D constructs can healthier tend to our maturing people with least destructive surgeries and at the same time trimming down the use of animals in different studies.

Biofabrication: Opening the power of living cells at Microsoft Research

Biofabrication is definitely a new word to all of us but I am certain that this could be the next greatest thing for the entire world. At the present time, when there are so many non Eco-friendly creations like plastics that are present in our environment, this new word ‘Biofabrication’ really holds its worth and significance.

So what is it about biofabrication that makes it essential? Biofabrication is the invention of organs and tissues in a special way where it aids in healing sicknesses like cancer and all other health related matters in an instant. Biofabrication also produces good results on the additive manufacturing ideas also called 3D printing in which cells, fibers and gels are enhanced into a single production to substitute damaged or unhealthy tissues.

Professionals from dissimilar fields like medicine, science and engineering have joined forces simply because biofabrication is a budding field. They are united in creating new tools that will possibly be used to biomedical and biological applications. And because of these tools you can lessen the handling of tons of harmful materials that can be the source of great injury to our ecosystem.

Discussed here are some of the current and future application and its associated technologies: In Vitro Assays: Biofabrication can attest to be very helpful in building up microassays by only using a tiny amount of material. The next one is Scatfolds for tissue engineering: All the studies made in the development of biofabrication have formed an opening for the construction of biometric scatfolds where decent and clear cut stable architecture can be made.

The third on is biofabrication is currently seen contributing to the advancement of biotechnologies that helps in energy creation in potential biofuel industry and in the invention of animal free products. The last one is breast reconstruction: biofabrication is very functional in dealing with this deadly disease. Last December 4, 2014 in the New York City, a conference regarding biofabrication was held. The main theme of the conference was bioethics, living materials and bio design etc. and people from Microsoft attended as well as other professionals.

A man from Microsoft Research, Erin Smith, is currently working on merging wearable computing with biofabrication to produce machines that suggest particular health benefits.

Modern manufacturing concept

Biofabrication is defined as the ability of science to produce living and nonliving biological products coming from sources like living cells, molecules, extracellular matrices and biomaterials. There are three main disciplines that contribute to the emergence of biofabrication technology and these are biomaterial science, cell and development biology, and mechanical engineering.

In comparison to traditional medically oriented tissue engineering and organ printing, the industrial potentiality of biofabrication is really far beyond because in just a short term period, it is already essential in the production of highly predictive human cell-and-tissue-based technologies to discover drugs, its toxicity, environmental toxicology assays, and complex in vitro models of human development and diseases.

In the long run, the biofabrication technology can be very essential in contributing to the development of novel biotechnologies to sustain energy production for the future biofuel industry and transform traditional animal-based agriculture through the invention of animal-free food, leather and fur products.

Biofabrication will be the dominating technological platform and new paradigm for 21st century manufacturing. This review will help in the development of global biofabrication research community that is a great factor in science.


1. Biofabrication: a 21st century manufacturing paradigm. Mironov V1, Trusk T, Kasyanov V, Little S, Swaja R, Markwald R. 1Medical University of South Carolina, Charleston, SC 29425, USA.


3. Biofabrication: Unlocking the power of living cells at Microsoft Research

what_is_biofabrication.txt · Last modified: 2015/10/23 02:57 by elena